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Men with low testosterone levels (low T) considering testosterone replacement therapy (TRT) at Rejuvime Medical have several questions about the treatment. One of the most common questions is how long it takes before they notice the results of TRT. The answer is some symptoms of low T take longer to improve than others.

Low T symptoms can include a lack of energy and productivity, reduced sex drive, depression, and brain fog. Without sufficient testosterone levels, you may also have difficulty building lean muscle, despite working out regularly. Exercise routines that once kept you trim and fit might no longer accomplish those goals.

How Soon Will You Notice Results?

Different therapy methods are available for testosterone replacement therapy, including injections, pellets, and topical creams. Testosterone shots tend to work most efficiently, and the timelines described in this blog post are based on injections. The results won’t occur overnight, but you’ll see some of the benefits in just a few weeks.

Testosterone injections also provide the most control over your dosage and the opportunity to monitor how they affect you. Each time you come in for an injection, we can also address any issues or concerns you may have.

Here’s how soon you can expect TRT to work for various low T symptoms:

Sex Drive

Testosterone injections improve your libido more quickly than other symptoms. You may start to notice your sex drive ramping up within 3 to 4 weeks before plateauing at about 6 weeks. Continued testosterone replacement therapy will maintain those results. If you’re having trouble getting or maintaining an erection, it can take several more weeks before seeing the results of TRT.

Energy Levels

Increased energy and stamina start occurring after about 3 months. You’ll notice continued improvement for many weeks after that.

Muscle Mass

Changes to your body’s composition, such as increased lean body mass and muscle strength, along with reduced fat, start emerging between months 3 and 4 after starting treatment. These changes begin leveling off after 6 to 12 months, but you can still see gradual changes with regular exercise and long-term use of TRT.


If you’ve been experiencing mood swings or have felt depressed, you can expect to notice improvements about 6 weeks after starting TRT injections. It may take 6 months to experience the full effects of the treatment. It’s also important that you consult your primary care physician if your depression persists or gets worse.

Will These Results Last?

If testosterone replacement therapy is right for you, you’ll typically be on it long term. After some time, you may have more energy, increase your sex drive, and feel better overall. Our hormone specialists at Rejuvime Medical monitor your testosterone levels throughout your treatment and discuss the nature of your symptoms to ensure you continue to benefit from the treatment.

If you’re ready to alleviate your symptoms of Low T, we’re happy to talk with you about your options. You can request a consultation using our online form or call us at (225) 960-1580 to schedule an appointment with one of our hormone specialists.

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