Men with low testosterone levels (low T) considering testosterone replacement therapy (TRT) at Rejuvime Medical have several questions about the treatment. One of the most common questions is how long does it take for testosterone replacement therapy to work. The answer is some symptoms of low T take longer to improve than others.

How Long Does It Take for TRT To Work?

The results won’t occur overnight, but you’ll see some TRT benefits in just a few weeks if you’re taking TRT injections.

TRT can be administered as pellets, topical creams, or injections, and the method you choose affects how soon you will see your results.

  • Pellets are placed just below the skin and gradually release testosterone into the bloodstream.
  • With topical creams, your skin absorbs the testosterone over several hours.
  • Testosterone shots work most efficiently, allowing you to have the most control over your dosage and monitor how they affect you. Each time you come in for an injection, we can also address any of your issues or concerns.

Here’s how soon you can expect TRT injections to work for various low T symptoms:

Sex Drive

Testosterone injections improve your libido more quickly than other symptoms. You may start to notice your sex drive ramping up within 3 to 4 weeks before plateauing at about 6 weeks. Continued testosterone replacement therapy will maintain those results. If you’re having trouble getting or maintaining an erection, it can take several more weeks before seeing the results of TRT.

Energy Levels

Increased energy and stamina start occurring after about 3 months. You’ll notice continued improvement for many weeks after that.

Muscle Mass

Changes to your body’s composition, such as increased lean body mass, improved muscle strength, and reduced fat, start emerging between months 3 and 4 after starting treatment. These changes begin leveling off after 6 to 12 months, but you can still see gradual changes with regular exercise and long-term use of TRT.

Mood

If you’ve been experiencing mood swings or have felt depressed, you can expect to notice improvements about 6 weeks after starting TRT injections. It may take 6 months to experience the full effects of the treatment. It’s also important that you consult your primary care physician if your depression persists or gets worse.

How Long Does Testosterone Stay in Your System?

How long TRT stays in your system varies depending on how it is administered and individual factors, such as your metabolism, age, and overall health. Injectable testosterone is typically administered every 1 to 2 weeks. The therapy aims to maintain testosterone levels within a normal range, and we monitor you regularly to assess testosterone levels and adjust treatment as necessary.

Will These Results Last?

Testosterone replacement therapy results are long-lasting if TRT is right for you. After some time, you may have more energy, enjoy an increased sex drive, and feel better overall. Our hormone specialists at Rejuvime Medical monitor your testosterone levels throughout your treatment and discuss the nature of your symptoms to ensure you continue to benefit from the treatment.

How Long Do You Stay on TRT?

TRT is a life-long treatment. If you stop taking it, your testosterone levels will drop. Some men with low T decide not to be treated. They may find other ways to increase their energy level or decide to live with the changes in their libido and body.

Getting Help for Your Low T

For many men, TRT is the best low T treatment. If you’re ready to alleviate your symptoms of low T, we’re happy to talk with you about your options. You can request a consultation using our online form or call us at (225) 960-1580 to schedule an appointment with one of our hormone specialists.

Updated 2024

6 Responses to How Long Does It Take Testosterone Replacement Therapy (TRT) to Work?

    • Holly Valentine says:

      Yes, these are concerning side effects. You should discuss with your medical provider as soon as possible.

    • Holly Valentine says:

      Injections have to be taken more frequently to achieve optimal levels, every 14 days is not often enough.

  • Jason says:

    How long to see effects if taking 80mg of Testosterone cypionate weekly? I feel more energy and strength at the gym after taking 4 doses, but libido is still the same. Thank you!!

    • Rejuvime Medical says:

      Hi Jason! Thank you so much for your comment. It can take 6-8 weeks of consistency to reach therapeutic levels in your body. I would encourage you to stay consistent to help your body build your levels up! Please give us a call at 225.960.1580 if you have any other questions regarding TRT!

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