Many men and women who, in their prime, never worried about weight problems are often surprised when they start gaining weight in their 40s and 50s. “Middle-age spread” can sneak up on individuals who may lose confidence and begin worrying about their health as their weight increases.

What Causes Weight Gain After 40?

Lifestyle, metabolic, and hormonal changes are some of the reasons for weight gain. Women, for example, tend to gain weight during perimenopause and menopause as their estrogen levels fall. It’s not the dip in estrogen that causes weight gain, but the conditions associated with lower levels of estrogen—slower metabolism, less energy, and disrupted sleep patterns—that lead to increased total body fat and abdominal fat.

The same logic applies to men going through andropause, a period when low testosterone levels lead to changes that include being less active.

Rejuvime Medical offers hormone replacement therapy, semaglutide with B12, and tirzepatide in Baton Rouge, Metairie, and our other locations in Louisiana and Mississippi to address many of these concerns.

Why Midlife Weight Gain Is Significant

Weight gain and the change in body fat distribution that occurs at midlife are partly responsible for the greater risk of cardiovascular disease in postmenopausal women compared to younger women with active ovarian function. Cardiovascular disease is the leading cause of mortality in postmenopausal women. Increased belly fat in men is also linked to heart disease and other health concerns.

Weight loss after age 50 certainly can be more challenging than earlier in life for both men and women, but it’s possible and can help you recapture the energy you felt in your youth.


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How Semaglutide and Tirzepatide Can Help With Weight Management

Semaglutide and tirzepatide are injectable medications that help people with diabetes manage their insulin. These medications mimic natural hormones that slow digestion and make the stomach feel fuller, helping suppress the patient’s appetite. Medically monitored weight loss drugs like semaglutide and tirzepatide, when taken once weekly, have been shown to reduce patients’ initial body weight by almost 15%.

What Are Compounded Weight Loss Medications?

Our proprietary medications help patients optimize their metabolism, boost weight loss, and maintain the health of the metabolism, red blood cells, and nerves. One of the top compounding pharmacies in the country compounds our weight loss medications. They use an NABP-accredited manufacturer to source their semaglutide (which is not salt-based semaglutide sodium) and tirzepatide.

Benefits of Semaglutide & Tirzepatide Treatment

Medically monitored weight loss medications like semaglutide and tirzepatide help you manage and lose weight more effectively without intense exercise by achieving the following:

  • Helping you feel satiated longer 
  • Slowing the release of food through your digestive system 
  • Suppressing feelings of hunger 
  • Helping you adhere to a low-calorie diet 

Can Hormone Replacement Therapy Help You Lose Weight?

Even though hormone replacement therapy isn’t used directly as a weight loss treatment, fat reduction can be one of the welcome side effects of HRT. By regulating women’s estrogen levels, HRT can help boost metabolism, increase muscle mass, and reduce body weight when combined with physical activity and a nutritious diet. Because testosterone helps support muscle mass, bone density, fat burning, and overall energy, boosting T levels can also help reduce weight.

Hormone replacement therapy helps lower weight because:

  • It helps your body function more efficiently so you retain less toxins and water
  • Your body absorbs more minerals to improve fat burning
  • You feel more energetic, so you exercise and move around more

These effects, in turn, help to reduce fat and keep your weight down. Studies have linked hormone therapy for relieving menopausal symptoms with reduced body fat in older women who are also physically active.1 Researchers have also found that testosterone replacement therapy can support significant weight loss, reduced waist circumference, and BMI over the long term.2

Start Your Journey

If you want to learn more about hormone replacement therapy, semaglutide with B12, or tirzepatide for weight management and reversing the effects of aging, request a consultation at one of our clinics in the Southeast. We serve women and men from Baton Rouge, Lafayette, New Orleans, and throughout Louisiana and Mississippi. Use the online form or call us at (225) 960-1580 to schedule an appointment.



We invite you to join us online from the comfort and privacy of your own home, to discuss our effective medical treatments that can help you lose weight and eliminate stubborn fat!

July 24 | 5:30PM