Many men and women who, in their prime, never worried about weight problems are often surprised when they start gaining weight in their 40s and 50s. “Middle-age spread” can sneak up on individuals who may lose confidence and begin worrying about their health as their weight increases.
What Causes Weight Gain After 40?
NLifestyle, metabolic, and hormonal changes are some of the reasons for weight gain. Women, for example, tend to gain weight during perimenopause and menopause as their estrogen levels fall. It’s not the dip in estrogen that causes weight gain, but the conditions associated with lower levels of estrogen—slower metabolism, less energy, and disrupted sleep patterns—that lead to increased total body fat and abdominal fat.
The same logic applies to men going through andropause, a period when low testosterone levels lead to changes that include being less active.
Rejuvime Medical offers hormone replacement therapy and compounded semaglutide with B12 in Baton Rouge, Metairie, and our other locations in Louisiana and Mississippi to address many of these concerns. We also prescribe Wegovy® (semaglutide) and Zepbound® (tirzepatide) for metabolic optimization and weight loss.
Why Midlife Weight Gain is Significant?
Weight gain and the change in body fat distribution that occurs at midlife are partly responsible for the greater risk of cardiovascular disease in postmenopausal women compared to younger women with active ovarian function. Cardiovascular disease is the leading cause of mortality in postmenopausal women. Increased belly fat in men is also linked to heart disease and other health concerns.
Weight loss after age 50 certainly can be more challenging than earlier in life for both men and women, but it’s possible and can help you recapture the energy you felt in your youth.

Everyone responds to testosterone therapy differently, and some symptoms may be linked to other health concerns. That’s why it’s important to work with your primary care provider to understand what’s best for your overall health.
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Rejuvime Medical
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(225) 960-1580
Locations Across Louisiana and Mississippi
How can Semaglutide Help with Weight Management?
Semaglutide is an injectable medication originally developed to help people with diabetes manage blood sugar. It works by mimicking natural hormones that slow digestion and create a feeling of fullness, helping suppress appetite. When used as part of a medically monitored weight loss program, semaglutide taken once weekly has been shown to support significant weight reduction. In some cases, patients may see up to a 15% decrease in their initial body weight.
What are Medically Monitored Weight Loss Medications?
Our physician-guided weight loss programs include access to medications that help optimize metabolism, support fat loss, and maintain overall health. These prescription therapies are sourced through accredited pharmacies and undergo strict quality standards to ensure safety and effectiveness.





Benefits of Semaglutide Treatment
A medically monitored weight loss program that may include semaglutide can help you manage weight more effectively without relying on extreme exercise. Benefits may include:
- Helping you feel full longer
- Slowing the rate at which food leaves your stomach
- Reducing Hunger Cues
- Supporting adherence to a lower calorie diet
Can Hormone Replacement Therapy Help You Lose Weight?
Even though hormone replacement therapy isn’t used directly as a weight loss treatment, fat reduction can be one of the welcome side effects of HRT. By regulating women’s estrogen levels, HRT can help boost metabolism, increase muscle mass, and reduce body weight when combined with physical activity and a nutritious diet. Because testosterone helps support muscle mass, bone density, fat burning, and overall energy, boosting T levels can also help reduce weight.
Hormone replacement therapy helps lower weight because:
- It helps your body function more efficiently so you retain less toxins and water
- Your body absorbs more minerals to improve fat burning
- You feel more energetic, so you exercise and move around more
Studies show that hormone therapy, when combined with regular activity, may help postmenopausal women reduce body fat.
For men,
research proves that testosterone therapy has been linked to lasting weight loss, smaller waistlines, and improved BMI.
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Baton Rouge (Jefferson) Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.List Item 1
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Breanna Berard, FNP-BC Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.
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Mariah Butcher, FNP- C Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.List Item 1
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Ebony Eaglin, FNP-C Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.
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Anna Fisher, FNP-C Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.
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Claudia Guepet, FNP-C Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.
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Alli Hansell, FNP-C Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.
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Marisol Jobe, FNP-C Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.
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Lacee May, FNP-C Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.
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Taylor Parrish, FNP-C Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.
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Michelle Walker, FNP-C Write a description for this list item and include information that will interest site visitors. For example, you may want to describe a team member's experience, what makes a product special, or a unique service that you offer.
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